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    Clinical Panels

    NovoFocus™ CRC 2.0

    NovoFocus™ CRC 2.0 Test is a next generation sequencing (NGS)-based assay that analyzes 50 genes related to Colorectal Cancer (CRC) for clinically important alterations at the DNA level and some other genes for Microsatellite Instability (MSI) status. These genes are known to be relevant for the diagnosis and/or treatment of various CRC according to National Comprehensive Cancer Network (NCCN) guideline and the medical literature.

    Parameters

    NovoFocus™ CRC 2.0
    Cancer Type
    Colorectal Cancer
    Sample Type
    FFPE Blood /
    Plasma (Extracted DNA)
    Turnaround Time
    14 Calendar Days
    Novogene Quality Assurance
    Comprehensive Results

    NovoFocus™ CRC 2.0 interrogates the complete coding region of 50 genes and introns of 10 genes. It can detect genomic abnormalities (SNV, InDel, CNV and Fusion) and MSI and provide targeted therapy/immunotherapy options. Besides, it analyzes pharmacogenomics and provides chemotherapy options.

    Reliable Performance

    Comprehensive analytical validation has been completed and the test includes rigorous quality control measures.

    Competitive Price

    With leading-edge sequencing solutions and superior process efficiency, Novogene offers highly competitive prices for all our service.

    Who Benefit from NovoFocus™ CRC 2.0?

    NovoFocus™ CRC 2.0 is suitable for all CRC patients, especially for the following:

  • Patients newly diagnosed with Colorectal Cancer (CRC)
  • CRC patients with drug resistance to multiple types of chemotherapy
  • CRC patients planning to use targeted therapy
  • CRC patients who are treated with chemotherapies and would like to know the efficacy and toxicity of these drugs
  • Workflow

    What Clinical Information Does NovoFocus™ CRC 2.0 Provide?

    Provide the information about relevant biomarkers and genomic alterations to help match patients to targeted therapies.

    Provide the SNP information related to efficacy and toxicity of chemotherapies.

    Gene list

    50 genes on targeted therapy
    ABCG2
    AKT1
    ALK
    APC
    BRAF
    C8orf34
    CCND1
    CDK4
    CDK6
    DDR2
    DPYD
    EGFR
    ERBB2
    ERCC1
    FBXW7
    FGFR1
    FGFR2
    FGFR3
    GNA11
    GNAQ
    GSTP1
    HRAS
    JAK1
    JAK2
    JAK3
    KIT
    KRAS
    MAP2K1
    MAP2K2
    MET
    MTHFR
    MYC
    NRAS
    NTRK1
    NTRK2
    NTRK3
    PDGFRA
    PIK3CA
    POLD1
    POLE
    PTEN
    RAF1
    RET
    ROS1
    SMO
    TP53
    TSC1
    UGT1A1
    XPC
    XRCC1

    9 genes on chemotherapy
    ABCG2
    C8orf34
    ERCC1
    GSTP1
    MTHFR
    TP53
    UGT1A1
    XPC
    XRCC1